GPT and Nephropathy: In acute toxicity tests, mice were orally administered a non-lethal PM-D dose (2 g/kg) for 7 consecutive days; PM-D not only increased aspartate aminotransferase (AST) and alanine transaminase (ALT) levels but also increased related liver pathology indicators, including liver cell necrosis and damage [13], and caused biochemical and pathological kidney damage.