Fibroblast Growth Factor-23 (FGF-23) has emerged as a biomarker in cardiovascular research [30,31]—previous studies have shown that FGF-23 is an independent predictor of cardiovascular events in the community [32,33,34] and its association with atherosclerosis has been established [35,36], though its exact role remains unclear. The gene discussed is FGF23; the disease is atherosclerosis.