Vascular endothelial growth factor A (VEGF-A)-dependent endothelial cell sprouting (IC50 = 3.7 μM); notable antiproliferative activities against L5178Y (mouse lymphoma) tumor cell line (IC50 = 2.05 μM); no inhibitory activity for the protein kinase and weak activities against K-562, A2780 (human ovarian cancer line), and A2780CisR (cisplatin-resistant human ovarian cancer cells) with IC50 values of 50.3, 41.3, and 66.0 μM, with cisplatin used as the positive control (IC50 = 7.80, 0.80, and 8.40 μM). The gene discussed is WEE1; the disease is neoplasm.