Aspergillus-specific IgE ≥ 0.35 kUA/L on fluorescent enzyme immunoassay (EIA) has shown to be 99–100% sensitive for ABPA screening in adults with asthma, in comparison to Aspergillus skin prick test (SPT) with only an 88–94% sensitivity [155]; therefore, screening with Aspergillus SPT is only recommended if Aspergillus sIgE is not available [126]. This evidence concerns the gene IGHE and asthma.