More GMRGs, including diacylglycerol kinase beta (DGKB), diacylglycerol kinase iota (DGKI), acylglycerol kinase (AGK), aldo-keto reductase family 1 member B1 (AKR1B1), and aldehyde dehydrogenase 9A1 (ALDH9A1), exhibited more CNV amplifications in adrenocortical carcinoma (ACC), KICH, OV, and UCS (Figure 1B). The gene discussed is AKR1B1; the disease is adrenal cortex carcinoma.