TNNI3 and cardiovascular disorder: They can detect not only pathogens like Escherichia coli [33], Salmonella typhimurium [34], and the SARS-CoV-2 virus [35], which have extractable genetic information, but also substances closely related to human life, such as cardiac troponin I (cTn I), associated with cardiovascular diseases (CVDs) [36], and even non-biological substances like cocaine [37] and Pb2+ [38].