HOTAIR and pachyonychia congenita: For example, HOTAIR (HOX transcript antisense intergenic RNA), MALAT1 (Metastasis-associated lung adenocarcinoma transcript 1), HOTTIP (HOXA transcript at the distal tip), and PVT1 (Plasmacytoma Variant Translocation 1) have recently been found to be essential regulators linked to the progression of PC and have diagnostic and prognostic implications [26,27,28].