This study highlighted LINC00261 as a critical component of the LINC00261/miR105-5p/SELL axis, which influences immune cell function and patient survival in HCC [7], and explored how post-transcriptional regulatory mechanisms involving the LINC00261/miR105-5p/SELL axis influence immune dysfunction and overall survival in HCC patients. This evidence concerns the gene LINC00261 and hepatocellular carcinoma.