Moreover, a poor clinical prognosis and the onset of metastasis in CRC patients are strongly associated with increased expression levels of MALAT1 (Metastasis-Associated Lung Adenocarcinoma Transcript 1), HOTAIR (HOX transcript antisense intergenic RNA), and H19 (H19 Imprinted Maternally Expressed Transcript) [39]. The gene discussed is HOTAIR; the disease is colorectal carcinoma.