However, it is important to clarify that the function or role in the cancer biology of many genes, such as LINC00977, LINC02912, ASAP1-IT2, PGAP3, TCAP, ZPBP2, PNMT, BCAS3, ZMYND8, CCAT1, STARD3, PIP4K2B, FAM72C, TSHZ2, SRGAP2D, LINC00536, USP32, NEUROD2, LINC02584, CASC8, TTN, ANO1, RYR2, TRPS1, PRNCR1, LTO1, MSI2, TOP6BL, CCAT2, MICU1, SYNE1, NSD3, BPTF, FBXL20, WIPF2, FBXO47, PVT1, TANC2, PKHD1L1, and DNAAF11, remains unclear. The gene discussed is LTO1; the disease is cancer.