The TCGA PRAD dataset analysis of BAP1 gene expression revealed an increase in BAP1 expression in the tumor samples when compared to adjacent or paired normal tissues (Figure 4A), moreover, the BAP1 gene upregulation was significantly correlated with increased Gleason score (Figure 4B) and common genomic aberrations such ERG fusion, ETV1 fusion, ETV4 fusion, FL1 fusion, FOXA1 mutation, IDH1 mutation, and SPOP mutation (Figure 4C). The gene discussed is SPOP; the disease is neoplasm.