Among the proteins that characterize the urinary profiles of HD with greater IF (≥40%), we found Carboxypeptidase M (CPM), Hepatitis A virus cellular receptor 2 (HAVCR2), SLAM family member 5 (CD84), Phospholipase DDHD1 (DDHD1) and Syndecan-1 (SDC1). Here, SDC1 is linked to Huntington disease.