IL4 and asthma: The main molecular pathways of asthma include T2 inflammation, mediated by Th2 and ILC2 cells, eosinophils, and the cytokines IL-4, IL-5, and IL-13, as well as non-T2 inflammation, mediated by neutrophils, macrophages, and the cytokines IL-1, IL-6, and IL-17.