EP300 and hepatocellular carcinoma: Furthermore, the compound interacts with molecular targets and pathways involved in hepatocellular carcinoma HCC, including PIK3R1 (key player in the PI3K pathway), RELA (subunit of NF-κB), EGFR (epidermal growth factor receptor) and EP300 (histone acetyltransferase), all of which are essential for cellular functions like survival, proliferation and apoptosis [31,32].