The in silico analysis that we performed predicted the possible participation of several common pathways including the focal adhesion pathway, adherens junction pathway, neurotrophin signaling pathway, endoplasmic reticulum processing pathway, actin cytoskeleton regulation, RNA transport, apoptosis, and dopaminergic synapse that could play an important role in SCA7 and are consistent with previous knowledge in other neurodegenerative diseases. This evidence concerns the gene BDNF and neurodegenerative disease.