Several groups have confirmed genetic variations (SNPs, mutations, and trinucleotide repeat (TNR) expansion) in candidate genes, including COL8A2, TCF4, SLC4A11, AGBL1, ZEB1, LOXHD1, XRCC1, FAS, and FASLG, to be in an association with early-onset and/or late-onset FECD [30,39,41,42,43,44,45,46,47,48]. This evidence concerns the gene AGBL1 and Fuchs endothelial corneal dystrophy.