Another single-cell RNASeq analysis of MM cells obtained from BM biopsies of nine RRMM and pleural effusion or ascites from four EMM patients identified differentially overexpressed genes involved in proliferation/cell-cycle progression, glycolysis, oxidative phosphorylation, proteasome, and antigen presentation genes in EMM versus higher levels of TNFa-induced NFkB pathway genes in BM-derived MM [83]. Here, NFKB1 is linked to Miyoshi myopathy.