YTHDF3 and colorectal cancer: Specifically, a negative feedback loop involving the LncRNA GAS5-YAP-YTHDF3 axis has been identified, wherein LncGAS5 promotes YAP degradation through ubiquitination and intracellular translocation, while YAP upregulates YTHDF3 expression, leading to the degradation of m6A-modified LncGAS5 and ultimately inhibiting YAP degradation, thereby contributing to the progression of colorectal cancer [98].