In our previous work, we observed a significant increase in CD4+ T cells and Th1 cells in luminal A breast cancer compared to luminal B. Additionally, a slight positive correlation between Ki-67, a marker of cellular proliferation, and Th1 cells was identified within the luminal A subtype, suggesting that Th1-mediated immune responses might influence the proliferative capacity of these tumors [56]. This evidence concerns the gene MKI67 and breast carcinoma.