LTF and xerostomia: Xerostomia and other saliva production disorders, often associated with decreased IgA levels, can lead to increased Candida colonization.(29) Previous studies have pointed out that many salivary components may inhibit fungal populations.(30) Molecules such as lysozymes, lactoferrins, histatins, peroxidases, calprotectins, and salivary IgA prevent fungal adherence to prosthetic surfaces.