Despite advances in the diagnosis and treatment of MEN1, life expectancy is reduced compared to the rest of the population, with the average age of death of 55–60 years, with the cause in 50–70% of cases being related to the disease itself.2 Enteropancreatic tumors, such as gastrinomas and carcinoid tumors, are the main causes of death in patients with MEN 1.5 This evidence concerns the gene MEN1 and multiple endocrine neoplasia.