Moreover, fucosylated kininogen was not detected in all samples to the extent that it was impossible to compare methylation models with Doylestown Plus.[25] Fourth, previous early detection studies have found that early detection models based on DNA methylation were associated with cancer prognosis.[26] Currently, the follow‐up time for patients included in our study is relatively short, and the recurrence events are not yet sufficiently mature for related analyses. The gene discussed is KNG1; the disease is cancer.