Mounting evidence indicates that unpaired fructose triggers gut formation of asthma-triggering immunogens by inducing gut fructosylation/modification of partially digested dietary proteins and gut hormones/incretins (GIP, GLP-1)(21,27–30), and by inducing changes in the gut microbiome (dysbiosis) which produces asthma-triggering metabolites(25,31–33). The gene discussed is GIP; the disease is asthma.