To investigate the role of EMB in stroke‐induced microglial inflammatory transformation, microglia modified with the EMB gene were exposed to OGD, and the level of IL‐6 and TNF‐α was higher in the supernatant of microglia overexpressing EMB, while a lower level of IL‐10 and TGF‐β compared to EMB knockdown microglia (Figure 3A–D). This evidence concerns the gene TGFB1 and stroke disorder.