GPT and insomnia measurement: Among them, 20 AEs of interest were identified, including Rash, Alopecia, Fatigue, Dry skin, Stomatitis, Anorexia, Nausea/Vomiting, Constipation, Myalgia/Arthralgia, Aspartate aminotransferase (AST) increased, Alanine aminotransferase (ALT) increased, Creatinine increased, Anemia, White blood cell decreased, Platelet count decreased, Dyspnea, Pneumonia, Insomnia, Chest pain, and Interstitial lung disease (ILD).