In accordance with our functional observation of reduced invasiveness of miR‐29c‐3p‐transfected endometriotic cells, a significant upregulation of its target genes CDK6, p21 (CDKN1), PTEN, TCF7L1, TCF7L2, COL4A2, and N‐Cadherin was detected in lesions of deep endometriosis compared to control endometrium. This evidence concerns the gene TCF7L1 and endometriosis.