Moreover, a significant downregulation of several potential targets, including CDK6, BCCIP, PTEN, TCF7L1, TCF7L2, ROBO1, COL4A2, E‐Cadherin, and N‐Cadherin, was observed in the transfected cells and endometriosis patients. The gene discussed is TCF7L2; the disease is endometriosis.