However, at the 95th percentile of SHBG values, there was 46% higher odds of hypothyroidism (OR 1.46, 95% CI 0.33–6.54) and an over tenfold increase at the 99th percentile (OR 10.07, 95% CI 1.94–52.45, p=0.006). Here, SHBG is linked to hypothyroidism.