According to the Pulmonary Embolism Severity Index (PESI) criteria and risk stratification for pulmonary embolism, the patient was placed in the intermediate-high risk group, due to high troponin and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels and right ventricular dysfunction, without hemodynamical instability. The gene discussed is NPPB; the disease is pulmonary embolism.