discovered that Eupatilin, a flavonoid isolated from Artemisia annua, possesses the ability to impede extracellular matrix (ECM) degradation and ameliorate senescence in nucleus pulposus (NP) cells by suppressing TNF‐α‐induced MAPK/NF‐κB activation, ultimately exerting a remarkable effect in delaying the progression of IDD [9]. This evidence concerns the gene TNF and intervertebral disk degenerative disorder.