The study investigates the effects of genistein consumption as a supplement on body mass index (BMI), lipid profile, blood pressure (systolic pressure (SBP) and diastolic pressure (DBP)), fasting glucose, insulin-related indicators (fasting insulin and homeostatic model assessment of insulin resistance (HOMA-IR)), homocysteine (HCY), and C-reactive protein (CRP) in the overall population. This evidence concerns the gene CRP and Insulin resistance.