Fever, cough, sweats; wife had mono syndrome 1–2 wk priorNo pharyngitis, no palpable LN or HSMWBC 13K, L 69%, reactive lymphocytes; increased liver enzymes and LDHEBV VCA IgG+ IgM+; EA Ab−; EBNA+; HSV-1/2 IgM+ IgG−No hepatitis A/B/C panel or Toxo AbCT chest: old granulomatous disease. The gene discussed is CD40LG; the disease is hepatitis A virus infection.