MKI67 and hepatocellular carcinoma: Figure 3 shows the comparisons of the ROC curves in the training and test sets. The DCAs for the combined model in the training set and test set are shown in Supplementary Figure S2. The combined model demonstrated good clinical utility by DCA analysis in both the training and test sets. Calibration curves of both the training and test sets are presented in Supplementary Figure S3, which showed predicted and actual probabilities of HCC with high Ki-67 expression.