Among non-ADRD/MCI patients, the surgery group had higher rates of hypertension (58.93% vs 48.52%), dyslipidemia (6.13% vs 5.12%), depression (21.02% vs 13.53%), and OSA (46% vs 22.68%), and lower rates of IHD (7.08% vs 10.54%) and GLP-1 drug use (0.4% vs 1%) than the control group. This evidence concerns the gene GCG and depressive symptom measurement.