CCMH affects the ROS pathway, ubiquitin-proteasome system, PI3K/Akt, and MAPK signaling pathways. CCMH significantly increases the level of ROS in gastric cancer cells, and NAC can reverse the effect of CCMH on ROS levels in gastric cancer cells. NAC antagonizes the apoptotic induction of CCMH. CCMH can significantly reduce the activity of the 20S proteasome in gastric cancer cells. CCMH also regulates the expression of key proteins in the PI3K/Akt and MAPK signaling pathways. Here, AKT1 is linked to gastric cancer.