RBCK1 and pancreatic adenocarcinoma: Ferroptosis activator imidazole erastin (IKE) upregulates its E3 Ub ligase RANBP2-type and C3HC4-type zinc finger containing 1 (RBCK1), and the knockdown of RBCK1 enhances the cytotoxic effect of IKE on PAAD cells (134).