CD274 and cancer: KEGG pathway enrichment analysis of the target genes of these SNPs revealed significant enrichment in cancer‐related pathways, such as “Pathways in Cancer,” “MAPK Signaling Pathway,” and immune‐related pathways including “Th1 and Th2 Cell Differentiation” and “PD‐L1 Expression and PD‐1 Checkpoint Pathway in Cancer” (Figure5A).