Gal-1 present on CTC surfaces can attach to molecules like CD44, CD326, P-selectin, and membrane glycoprotein complexes (GPIIb/IIIa), facilitating tumor cell clustering, attachment to the ECM and endothelial cells, and retention in the capillaries of secondary organs, ultimately leading to the formation of metastatic lesions [8]. Here, GAL is linked to neoplasm.