Our GWAS of children's own genotypes and childhood asthma identified associations in ZPBP2 (on chromosome 17q21.1), a gene predicted to be involved in the assembly of the cap‐like structure covering the head of a sperm (acrosome) and in the process through which a sperm binds to the extracellular matrix (zona pellucida) surrounding an oocyte. This evidence concerns the gene ZPBP2 and childhood onset asthma.