For discriminating tuberculosis patients with ATDILI from those without ATDILI, ROC curve analysis revealed that NAT2 demethylation index of 0.52 yielded a sensitivity of 73.10, a specificity of 63.30, a positive predictive value (PPV) of 61.11, a negative predictive value (NPV) of 67.86, and an AUC of 0.741 (95% CI 0.646, 0.837; P < 0.001) (Fig. 4A). The gene discussed is NAT2; the disease is tuberculosis.