SMARCA4 and glioblastoma: In BRG1KO cells restored with wild‐type BRG1, IV‐255 combined with TMZ resulted in intense γH2AX staining (Figure 5B), while γH2AX staining expressing the Tyr1497Phe mutant again demonstrated the requirement for the Tyr1497 residue in the BRD for V‐255 sensitization of GBM cells for TMZ‐induced damage.