Although, to some surprise, this study has not been followed up by more in-depth mechanistic reports, several publications as well as genome-wide association studies (GWAS) have indeed predominantly associated GPR61 gene locus with type 2 diabetes, increased BMI, and body fat composition (https://www.ebi.ac.uk/gwas/genes/GPR61) (Yuan et al, 2014; Felix et al, 2016). This evidence concerns the gene GPR61 and type 2 diabetes mellitus.