The expression of β-adrenergic receptors in human GC tissues and their correlation with clinical outcomes is examined in a substantial number of studies.12,38,42,43 Koh et al. showed that in 162 patients with stage I–III GC, high ADRB2 expression was significantly associated with pT, pN, venous invasion, and tumor stage. The gene discussed is ADRB2; the disease is neoplasm.