PROMIS Depression was significantly correlated with the GAD-7 (r = 0.71, p = < 0.0001) and ASWS (r = 0.48, p = < 0.0001), and medical chart documentation of depression and sleep involvement (r = 0.24, p = 0.02) were also significantly related. The gene discussed is GAD1; the disease is depressive symptom measurement.