Histopathologic efficacy determinations were Grade 1, Grade 2, and Grade 3 in 49 (52%), 12 (13%), and 34 (36%) patients, respectively, with median pre-NACRT PNI, NLR, PLR, LMR, CAR, PIV, SII, p53, and squamous cell carcinoma (SCC) antigen values of 49.1 (range: 0–62 .6), 2.05 (range: 0.78–5.73), 142.5 (range: 20.1–464.6), 4.49 (range: 1.59–14.88 g), 0.03 (range: 0–2.20), 168.5 (range: 38.0–2586.0), 488622 (range: 115986–2547851), 0 .4 (range: 0.4–264.0), and 1.4 (range: 0.4–6.0), respectively. Here, SERPINB3 is linked to squamous cell carcinoma.