Since transcriptomic datasets from human angiotropic melanomas are not currently available, we mined public transcriptome datasets of human skin melanoma (The Cancer Genome Atlas–skin cutaneous melanoma [TCGA-SKCM], where “angiotropic melanoma” is not annotated) to examine relationships between expression levels of PTPN11 (codes for the SHP2 protein) and expression levels of vascular regulators analyzed in mouse B16F10 tumors. This evidence concerns the gene PTPN11 and cutaneous melanoma.