In cohort 1, all 3 patients who received IFN-γ and a DLI achieved complete molecular, cytogenetic, and measurable residual disease–negative CRs (MRDneg CRs) with conversion to full donor chimerism, coincident with the development of steroid-sensitive GVHD (Figure 2, A–C). This evidence concerns the gene IFNG and graft versus host disease.