The LAR was more and found to be better in predicting need of inotropes among patients diagnosed with both sepsis and ARF in comparison to lactate alone (AUC: 0.849 v/s 0.810), SOFA score (AUC: 0.849 v/s 0.609), albumin alone (AUC: 0.849 v/s 0.710). The gene discussed is ALB; the disease is Sepsis.