The AUC for LAR (0.849) was better than that of albumin alone (0.810), lactate alone (0.766), and SOFA score (0.609), with the Youden index of LAR (0.69) being superior to that of lactate alone (0.41) and SOFA score (0.18), suggesting that LAR has better sensitivity and specificity for the need for inotropes in patients with sepsis and ARF than the SOFA score and lactate alone. Here, ALB is linked to Sepsis.