ARPC3/ARPC5L/ARPC5/ARPC2/ARPC4/ARPC1A/ACTL8/ACTL6A/ACTR6/ACTR5/ACTR8/ACTR1B/ACTR3/ACTR10/ACTR3B/ACTR2/ACTR1A were significantly overexpressed in HCC tissues more than in normal liver tissues, according to a combination of the analysis results of The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) databases (Figure 1; Supplementary Figure S1). The gene discussed is ACTR2; the disease is hepatocellular carcinoma.