ITGB3 and Alzheimer disease: From this analysis, we identified five FA-related key genes in OS (ITGB3, LAMC1, COL6A3, ITGA8, and PDGFRB) (Figure 4C) and five FA-related key genes in AD (ITGB3, ITGA4, LAMB1, ITGA8, and LAMA4) (Figure 4D).