When comparing all tumours with GC excess (n=15) to the remaining inactive and non-GC-secreting tumours (N=28), LEF-1 expression was significantly higher in GC-producing tumours (comprising GC and GCA) compared to non-GC-producing tumours with a median H-score of 70 (Figure 6D), but we did not observe a significant difference for CTNNB1 (Figure 6E) or GR (Figure 6F) expression in our dataset, respectively. Here, LEF1 is linked to neoplasm.