Diagnosis of APS was made as anticardiolipin antibody IgM was slightly positive at 16 micrograms of IgM antibody (normal range is ≤ 12) and anti-beta2-glycoprotein IgG was positive at 58 micrograms of IgG antibody (normal range is ≤ 20) in the setting of venous thrombosis. Here, CD40LG is linked to autoimmune polyendocrinopathy.