Studies have shown that sumac extract caused overexpression of caspase‐3 and a decrease in bcl‐2 (Gabr and Alghadir 2021), and increased the levels of apoptosis‐related factors such as Bax/bcl‐2 ratio and cleaved caspase‐3 and ‐9 activity (Kim et al. 2019), thus activating the apoptotic process and significantly inhibiting cancer cell growth, proliferation, and viability. This evidence concerns the gene BCL2 and cancer.