AIM2 and kidney disorder: Five main types of inflammasome have been identified, the NOD-like receptor thermal protein domain associated protein 4 (NLRP4), NOD-like receptor thermal protein domain associated protein 3 (NLRP3), NOD-LRR family with CARD 1 (NLRC1), ice-protease activating factor (IPAF), and absent in melanoma 2 (AIM2) inflammasomes, among which the NLRP3 inflammasome plays a central role in kidney diseases.